Childhood Leukaemia International Consortium (CLIC)

The Childhood Leukaemia International Consortium (CLIC) aims to overcome analytic constraints, such as limited sample size, in studies investigating the causes of childhood leukaemia.

CLIC was established in 2006 in collaboration with University of California, Berkeley (UCB) and the International Agency for Research on Cancer (IARC)

The Consortium is bringing together scientists from all over the world to try and work out what causes childhood leukaemia.

Members of CLIC represent 14 studies of childhood leukaemia spread across 10 countries – USA, Canada, Brazil, United Kingdom, France, Italy, Germany, South Korea, Australia and New Zealand. Discussions are taking place with a number of other study groups who are interested in joining the Consortium.

The Consortium is gathering cases from around the world to pool data on factors associated with childhood leukaemia risk. This will help to increase the certainty of any associations which have been reported. This includes such factors as environmental and (parental) occupational exposures, birth characteristics and immunity and infection.

In addition, CLIC aims to study gene-environment interactions in the causation of leukaemia. So far it has recruited around 9,000 cases and 16,000 controls. DNA samples are available for about half of these.

We are supporting this excellent international endeavour by funding the costs of CLIC meetings, which take place twice a year. The first meeting took place in San Francisco in November 2007. The second was held in San Diego in April 2008.

Visit CLIC's website.

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