At the moment, we don’t know the cause of the blood cancers myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML) in many children. But in some rare cases of MDS/AML more than one family member is affected. These family sets give us valuable data in the search to identify the genetic factors in these diseases. In this project, Dr Tom is working with 26 such families to characterise these genetic mutations.
Rare blood cancers affecting more than one family member could help us discover what’s at the root of the genetic mutations causing them. This project is studying 26 affected families to help us learn more.