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One of the hardest things about finding a cure for cancer is that many forms don’t respond well to treatment. We’re looking at why a particular kind of high-risk neuroblastoma that affects children resists attempts to treat it, so we can develop new ways to beat it, and give children a better chance to survive it and live longer lives.
High-risk neuroblastoma develops resistance to treatment, so children affected by it often relapse. We’re looking at what makes tumours develop resistance, so we can overcome it.
This research project on high-risk neuroblastomhas been successfully completed. Your donations allow us to fund ground-breaking research that can improve treatments given to children with cancer. Thank you. Your help allows us to continue to find ways to drive up the chances of survival for children with cancer and reduce the toxic side effects that can affect the rest of their lives.
CRISPR-based genome-wide knockout and overexpression screens to identify acquired resistance mechanisms to ALK inhibition in neuroblastoma
Dr Suzanne Turner
University of Cambridge
Cambridge CB2 0QQ
14 November 2016
3 years
£223,310
Development of ‘seek and destroy’ system against neuroblastoma
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Related research- Helen BryantNeuroblastoma has a ‘high-risk’ form which, despite using every treatment available, means that some children can’t be cured. Some
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