Research
2019 Research Grant Call: £3 million
We’re proud to have awarded £3 million in research grants for childhood cancer causes and prevention.
Project Details
- In 2019, £3.2 million funded fifteen projects researching childhood cancer causes and prevention.
- Grant Call
- 2019
- Funding Total
- £3,265,328
- Projects Funded
- 15
- Awards made
- 29/11/2019
Overview
Children with Cancer UK invited proposals for research projects and clinical PhD studentships that addressed improved treatment for and survival from childhood and young person cancer and into improved quality of ongoing life.
- Deadline for preliminary proposals: 5th April 2019
- Received 50 preliminary proposals
- Following triage by our Scientific Advisory Panel, 31 applicants were invited to submit full proposals.
- Final review was held on 26th & 27th February 2020
- Grants announced on 29 November 2019
Our panel included internationally respected experts in childhood cancer research and survivorship
- Dr Chris Halsey
- Dr Lynley Marshall
- Dr Nick Goulden
- Professor Roderick Skinner
- Chair: Professor Geoff Pilkington
The following 15 projects were awarded grants, totalling £3,265,328:
- Professor Chris Jones
- Host institution: Institute of Cancer Research
- Grant Title: Evolutionary dynamics of MEK inhibitor sensitivity and resistance in diffuse midline glioma
- Grant total: £349,393
- Professor Kathy Pritchard-Jones
- Host institution: UCL Great Ormond Street Institute of Child Health
- Grant Title: International benchmarking of childhood cancer survival by stage
- Grant total: £349,746.50
- Dr Marc Mansour
- Host institution: UCL Cancer Institute
- Grant Title: A novel immunotherapy target in T-cell acute lymphoblastic leukaemia (T-ALL)
- Grant total: £349,746.50
- Dr Claire Clarkin
- Host institution: University of Southampton
- Grant Title: Developing 3-dimensional multicellular models of osteosarcoma
- Grant total: £49,984
- Professor Mike Hawkins
- Host institution: University of Birmingham
- Grant Title: Establish a comprehensive surveillance system for adverse health outcomes in British survivors of childhood, teenage and young adult cancer
- Grant total: £349,982.37
- Professor Veronica Kinsler
- Host institution: UCL Great Ormond Street Institute of Child Health
- Grant Title: Identification of new therapies for melanoma in congenital melanocytic naevi – a universally fatal paediatric tumour
- Grant total: £249,755.76
- Professor Anthony Chalmers
- Host institution: University of Glasgow
- Grant Title: Increasing the susceptibility of neuroblastoma cells to radiotherapy by targeting glycolysis and lipogenesis
- Grant total: £249,774
- Dr Sam Behjati
- Host institution: Wellcome Sanger Institute
- Grant Title: Developmental states of localised and metastatic osteosarcoma cells – a knowledge bank for novel biomarkers and therapeutic approaches
- Grant total: £349,418.96
- Professor Julie Irving
- Host institution: Newcastle University
- Grant Title: Optimising the use of repurposed drugs to improve the treatment of children with ALL
- Grant total: £213,259
- Professor Steve Clifford
- Host institution: Newcastle University
- Grant Title: SMILE: An International network for Medulloblastoma Survivorship and Late-Effects
- Grant total: £348,783.27
- Professor John Anderson
- Host institution: UCL Great Ormond Street Institute of Child Health
- Grant Title: Pilot to develop CRISPR library screen for enhanced function of G-D-T cells in paediatric solid cancers
- Grant total: £49,929.66
- Dr Macarena Oporto Espuelas
- Host institution: UCL Great Ormond Street Institute of Child Health
- Grant Title: Identification of novel surface antigen targets for CAR T cell strategies in paediatric Acute Myeloid Leukaemia stem cells
- Grant total: £220,000
- Dr Defne Saatci
- Host institution: UCL Great Ormond Street Institute of Child Health
- Grant Title: Investigating Late Effects of Surviving Childhood Cancer
- Grant total: £216,963.40
- Dr John Murphy
- Host institution: University of Westminster
- Grant Title: A pilot Investigation of the ZFP36L1 protein as a candidate therapeutic target in osteosarcoma cells
- Grant total: £14,013
Memberships
Children with Cancer UK is a member of the Association of Medical Research Charities (AMRC), which sets minimum standards of good practice to which member charities must adhere in their grant-making, including policies on peer review. We are also a member of the National Cancer Research Institute (NCRI), a partnership of UK cancer funders.
Identifying new treatments for children with rhabdomyosarcoma
Related research – Dr Zoë Walters
Every year in the UK around 55 children are diagnosed with rhabdomyosarcoma, a cancer that affects connective tissues such
Accelerating the delivery of personalised treatment to children with neuroblastoma using MRI
Related research – Dr Yann Jamin
Using biomarkers has helped to improve response rates in adult cancers from 4-50%. We urgently need to get new treatments
Studying the role of ATRX in ALT positive cancers
Related research – Dr David Clynes
Cancers known as ALT positive include some incurable brain tumours that affect children. Our research project aims to uncover more
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