Causes

Dissecting the causative and collaborating roles of candidate genetic mutations in the pathogenesis of childhood ALL

Professor Tariq Enver, UCL Cancer Institute

Developing zebrafish models of inherited AML to interrogate secondary driver events

Dr Elspeth Payne, University College London

Role of aldehyde metabolism and DNA crosslink repair in in-utero genome stability and leukaemogenesis

Dr Ketan Patel, MRC Laboratory of Molecular Biology

Sequencing the unsequenceable: development of ground-breaking technologies to investigate the role of complex genomic sequences in childhood cancer

Professor Christine Harrison, Newcastle University

Characterising abnormal signalling pathway activation by PTPN11 mutations in Noonan syndrome and juvenile myelomonocytic leukaemia

Professor Anthony Whetton, University of Manchester

Identification of infections which may play a role in the aetiology of childhood acute lymphoblastic leukaemia (ALL)

Dr Ian Hampson and Dr Lynne Hampson, University of Manchester