Research hub
Pioneering science and innovation in cancer research is in our DNA
We’ve seen first hand how even a small breakthrough can make a significant difference in the survival chances of children and young people. That’s why we pour our fundraising into research, working closely with scientists and medical experts to improve diagnosis and find better, kinder treatments. Over the last 35 years, we’ve funded over 300 cancer research projects for children and young people.
Explore Inspiring Stories
Projects We Fund
Developing immunotherapy for childhood sarcomas.
Research Developing immunotherapy for childhood sarcomas. Some childhood cancers don’t respond well to chemotherapy, but there is hope in the…
Read more Developing immunotherapy for childhood sarcomas.
Childhood cancer immunotherapy using blood cells from umbilical cord blood.
Research Childhood cancer immunotherapy using blood cells from umbilical cord blood. Immunotherapy is an important new approach in the treatment…
Read more Childhood cancer immunotherapy using blood cells from umbilical cord blood.
Focusing on immunotherapy to target cancer cells without damaging healthy cells
Research Focusing on immunotherapy to target cancer cells without damaging healthy cells Developing new treatments for childhood cancers can be…
Read more Focusing on immunotherapy to target cancer cells without damaging healthy cells
Causes Cancers Blood
Finding out why some children get rare cancers of the blood. At the moment, we don’t know the cause of…
Read more Causes Cancers Blood
Unravelling the world-wide survival disparities in children, teenagers and young adults with leukaemia and lymphoma
Research Unravelling the world-wide survival disparities in children, teenagers and young adults with leukaemia and lymphoma This project is studying…
Read more Unravelling the world-wide survival disparities in children, teenagers and young adults with leukaemia and lymphoma
Focusing on immunotherapy to target cancer cells without damaging healthy cells
Research Focusing on immunotherapy to target cancer cells without damaging healthy cells Developing new treatments for childhood cancers can be…
Read more Focusing on immunotherapy to target cancer cells without damaging healthy cells
Childhood cancer immunotherapy using blood cells from umbilical cord blood
Research Childhood cancer immunotherapy using blood cells from umbilical cord blood Immunotherapy is an important new approach in the treatment of…
Read more Childhood cancer immunotherapy using blood cells from umbilical cord blood
Immunotherapy for infant and childhood MLL-rearranged acute lymphoblastic leukaemia
Research Immunotherapy for infant and childhood MLL-rearranged acute lymphoblastic leukaemia Young children with mixed lineage leukaemia rearranged infant acute lymphoblastic…
Read more Immunotherapy for infant and childhood MLL-rearranged acute lymphoblastic leukaemia
Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia
Research Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia Stem cell transplant is used as a treatment of last resort in young…
Read more Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia
Reducing toxicity in treatment for children with high-risk neuroblastoma
Research Harnessing a new immunotherapy approach to develop a treatment strategy for high-risk neuroblastoma. Neuroblastoma is one of the most…
Read more Reducing toxicity in treatment for children with high-risk neuroblastomaCauses
How do genes and environment work together to cause leukaemia?
Research How do genes and environment work together to cause leukaemia? We don’t know enough about what causes acute lymphoblastic…
Read more How do genes and environment work together to cause leukaemia?
Testing the role played by infectious exposure in childhood leukaemia development
Research Testing the role played by infectious exposure in childhood leukaemia development An established theory of childhood leukaemia development proposes…
Read more Testing the role played by infectious exposure in childhood leukaemia development
Investigating how childhood leukaemia develops
Research Investigating how childhood leukaemia develops The outlook for children diagnosed with B-cell acute lymphoblastic leukaemia (B-ALL) is poor because…
Read more Investigating how childhood leukaemia develops
Motorized traffic and risk of childhood leukaemia
Research Motorized traffic and risk of childhood leukaemia We need to find out more about the causes of leukaemia, the…
Read more Motorized traffic and risk of childhood leukaemia
Understanding the cancer risk in childhood and adolescent cancer survivors
Research Understanding the cancer risk in childhood and adolescent cancer survivors People who survive cancer during childhood and adolescence have…
Read more Understanding the cancer risk in childhood and adolescent cancer survivors
Understanding the genetics of paediatric glioblastoma
Research Understanding the genetics of paediatric glioblastoma International collaboration is often the best way to approach difficult research problems, and…
Read more Understanding the genetics of paediatric glioblastoma
Finding ways to protect unborn babies from genetic damage
Research Finding ways to protect unborn babies from genetic damage The genetic mutations that can lead to childhood leukaemia can…
Read more Finding ways to protect unborn babies from genetic damage
Analysing the precise genetic characteristics of tumours
Research Analysing the precise genetic characteristics of tumours Detailed analysis of the genetic characteristics of a child’s tumour can provide…
Read more Analysing the precise genetic characteristics of tumours
Identification of new genetic changes in rhabdomyosarcoma
Research Identification of new genetic changes in rhabdomyosarcoma Rhabdomyosarcoma (RMS) is a childhood cancer that develops in muscle, with 50 new…
Read more Identification of new genetic changes in rhabdomyosarcoma
Understanding the role genetic mutations play in acute myeloid leukaemia
Research Understanding the role genetic mutations play in acute myeloid leukaemia The second most common form of childhood leukaemia is…
Read more Understanding the role genetic mutations play in acute myeloid leukaemiaDiagnosis
Developing immunotherapy for childhood sarcomas.
Research Developing immunotherapy for childhood sarcomas. Some childhood cancers don’t respond well to chemotherapy, but there is hope in the…
Read more Developing immunotherapy for childhood sarcomas.
Childhood cancer immunotherapy using blood cells from umbilical cord blood.
Research Childhood cancer immunotherapy using blood cells from umbilical cord blood. Immunotherapy is an important new approach in the treatment…
Read more Childhood cancer immunotherapy using blood cells from umbilical cord blood.
Focusing on immunotherapy to target cancer cells without damaging healthy cells
Research Focusing on immunotherapy to target cancer cells without damaging healthy cells Developing new treatments for childhood cancers can be…
Read more Focusing on immunotherapy to target cancer cells without damaging healthy cells
Finding new ways to beat childhood neuroblastoma
Research Finding new ways to beat childhood neuroblastoma Neuroblastoma is one of the most common childhood tumours. We’ve been working hard…
Read more Finding new ways to beat childhood neuroblastoma
Early diagnosis of classical Hodgkin lymphoma
Research Early diagnosis of classical Hodgkin lymphoma Hodgkin lymphoma is one of the most common cancers affecting children and young…
Read more Early diagnosis of classical Hodgkin lymphoma
Developing a reliable, potentially life-saving test for Constitutional Mismatch Repair Deficiency
Research Developing a reliable, potentially life-saving test for Constitutional Mismatch Repair Deficiency Constitutional Mismatch Repair Deficiency is a rare inherited…
Read more Developing a reliable, potentially life-saving test for Constitutional Mismatch Repair Deficiency
New MRI techniques to improve diagnosis and monitoring of childhood cancer
Research New MRI techniques to improve diagnosis and monitoring of childhood cancer MRI scans are essential to help us diagnose…
Read more New MRI techniques to improve diagnosis and monitoring of childhood cancer
Diagnosing childhood medulloblastomas by improved MRI scans
Research Diagnosing childhood medulloblastomas by improved MRI scans The most common childhood brain tumours are called medulloblastomas. They are divided into…
Read more Diagnosing childhood medulloblastomas by improved MRI scans
Building on previous successes to improve treatment for acute lymphoblastic leukaemia
Research Building on previous successes to improve treatment for acute lymphoblastic leukaemia UK Acute Lymphoblastic Leukaemia Trial: UKALL 2011. Project…
Read more Building on previous successes to improve treatment for acute lymphoblastic leukaemia
Preserving the family medical history of cancer in children collected over 30 years
Research Preserving the family medical history of cancer in children collected over 30 years We were saddened to hear of…
Read more Preserving the family medical history of cancer in children collected over 30 yearsPrevention
Understanding the cancer risk in childhood and adolescent cancer survivors
Research Understanding the cancer risk in childhood and adolescent cancer survivors People who survive cancer during childhood and adolescence have…
Read more Understanding the cancer risk in childhood and adolescent cancer survivors
Early exposure to radio-frequency electromagnetic fields and cancer
Research Early exposure to radio-frequency electromagnetic fields and cancer We don’t know for certain whether radio waves produced by mobile…
Read more Early exposure to radio-frequency electromagnetic fields and cancer
Does air pollution pose a cancer risk for unborn children?
Research Does air pollution pose a cancer risk for unborn children? We don’t know enough about the link between road…
Read more Does air pollution pose a cancer risk for unborn children?
Studying the relationship between folate and leukaemia risk
Research Studying the relationship between folate and leukaemia risk We don’t know enough about what causes acute lymphoblastic leukaemia. Prof…
Read more Studying the relationship between folate and leukaemia risk
The effect of air pollution during pregnancy on childhood cancer risk
Research The effect of air pollution during pregnancy on childhood cancer risk Air pollution is known to cause a range…
Read more The effect of air pollution during pregnancy on childhood cancer risk
Studying the relationship between HIV, infection and childhood cancer
Research Studying the relationship between HIV, infection and childhood cancer Infections are known to cause various types of cancer, some…
Read more Studying the relationship between HIV, infection and childhood cancer
Learning why high-risk neuroblastoma resists treatment – to learn how to beat it
Research Learning why high-risk neuroblastoma resists treatment – to learn how to beat it One of the hardest things about…
Read more Learning why high-risk neuroblastoma resists treatment – to learn how to beat it
Why do second cancers occur within 5 years of diagnosis?
Research Why do second cancers occur within 5 years of diagnosis? The dramatically increased survival rates for childhood cancer in recent decades,…
Read more Why do second cancers occur within 5 years of diagnosis?
Does breastfeeding reduce risk of brain tumours in children?
Research Does breastfeeding reduce risk of brain tumours in children? We need to find new ways to prevent and treat…
Read more Does breastfeeding reduce risk of brain tumours in children?
Could a special diet help to treat or prevent childhood gliomas?
Research Could a special diet help to treat or prevent childhood gliomas? We desperately need new treatments for glioma, a…
Read more Could a special diet help to treat or prevent childhood gliomas?Survivorship
Developing immunotherapy for childhood sarcomas.
Research Developing immunotherapy for childhood sarcomas. Some childhood cancers don’t respond well to chemotherapy, but there is hope in the…
Read more Developing immunotherapy for childhood sarcomas.
Unravelling the world-wide survival disparities in children, teenagers and young adults with leukaemia and lymphoma
Research Unravelling the world-wide survival disparities in children, teenagers and young adults with leukaemia and lymphoma This project is studying…
Read more Unravelling the world-wide survival disparities in children, teenagers and young adults with leukaemia and lymphoma
Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia
Research Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia Stem cell transplant is used as a treatment of last resort in young…
Read more Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia
Reducing toxicity in treatment for children with high-risk neuroblastoma
Research Harnessing a new immunotherapy approach to develop a treatment strategy for high-risk neuroblastoma. Neuroblastoma is one of the most…
Read more Reducing toxicity in treatment for children with high-risk neuroblastoma
Investigating the long-term health impacts of surviving childhood cancer
Research Investigating the long-term health impacts of surviving childhood cancer As treatments improve, more children with cancer are surviving into…
Read more Investigating the long-term health impacts of surviving childhood cancer
INSTINCT: a network for improving treatments for high-risk childhood brain tumours
Research INSTINCT: a network for improving treatments for high-risk childhood brain tumours Brain tumours are the leading cause of death from…
Read more INSTINCT: a network for improving treatments for high-risk childhood brain tumours
Relapse-specific therapeutic vulnerability evaluation in childhood and young adult ALL (REVEALL)
Research Relapse-specific therapeutic vulnerability evaluation in childhood and young adult ALL (REVEALL) Survival for children and young people with acute…
Read more Relapse-specific therapeutic vulnerability evaluation in childhood and young adult ALL (REVEALL)
Helping prevent damage to the brains of children with cancer
Research Helping prevent damage to the brains of children with cancer Children with cancer often receive chemotherapy targeted at the brain to…
Read more Helping prevent damage to the brains of children with cancer
Building on previous successes to improve treatment for acute lymphoblastic leukaemia
Research Building on previous successes to improve treatment for acute lymphoblastic leukaemia UK Acute Lymphoblastic Leukaemia Trial: UKALL 2011. Project…
Read more Building on previous successes to improve treatment for acute lymphoblastic leukaemia
Customising support towards unmet psychosocial needs in young people with cancer
Research Customising support towards unmet psychosocial needs in young people with cancer In the same way that precision-medicine is offering…
Read more Customising support towards unmet psychosocial needs in young people with cancerTreatment
Developing immunotherapy for childhood sarcomas.
Research Developing immunotherapy for childhood sarcomas. Some childhood cancers don’t respond well to chemotherapy, but there is hope in the…
Read more Developing immunotherapy for childhood sarcomas.
Childhood cancer immunotherapy using blood cells from umbilical cord blood.
Research Childhood cancer immunotherapy using blood cells from umbilical cord blood. Immunotherapy is an important new approach in the treatment…
Read more Childhood cancer immunotherapy using blood cells from umbilical cord blood.
Focusing on immunotherapy to target cancer cells without damaging healthy cells
Research Focusing on immunotherapy to target cancer cells without damaging healthy cells Developing new treatments for childhood cancers can be…
Read more Focusing on immunotherapy to target cancer cells without damaging healthy cells
Focusing on immunotherapy to target cancer cells without damaging healthy cells
Research Focusing on immunotherapy to target cancer cells without damaging healthy cells Developing new treatments for childhood cancers can be…
Read more Focusing on immunotherapy to target cancer cells without damaging healthy cells
Childhood cancer immunotherapy using blood cells from umbilical cord blood
Research Childhood cancer immunotherapy using blood cells from umbilical cord blood Immunotherapy is an important new approach in the treatment of…
Read more Childhood cancer immunotherapy using blood cells from umbilical cord blood
Immunotherapy for infant and childhood MLL-rearranged acute lymphoblastic leukaemia
Research Immunotherapy for infant and childhood MLL-rearranged acute lymphoblastic leukaemia Young children with mixed lineage leukaemia rearranged infant acute lymphoblastic…
Read more Immunotherapy for infant and childhood MLL-rearranged acute lymphoblastic leukaemia
Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia
Research Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia Stem cell transplant is used as a treatment of last resort in young…
Read more Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia
Reducing toxicity in treatment for children with high-risk neuroblastoma
Research Harnessing a new immunotherapy approach to develop a treatment strategy for high-risk neuroblastoma. Neuroblastoma is one of the most…
Read more Reducing toxicity in treatment for children with high-risk neuroblastoma
Finding new ways to beat childhood neuroblastoma
Research Finding new ways to beat childhood neuroblastoma Neuroblastoma is one of the most common childhood tumours. We’ve been working hard…
Read more Finding new ways to beat childhood neuroblastoma
Early diagnosis of classical Hodgkin lymphoma
Research Early diagnosis of classical Hodgkin lymphoma Hodgkin lymphoma is one of the most common cancers affecting children and young…
Read more Early diagnosis of classical Hodgkin lymphomaOur media office
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