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Patient Story – Ryan

Ryan was diagnosed with NK/T-cell Lymphoma when he was 14 years old. His mum, Sarah, tells their story so far:

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Patient Story – Aimee

Aimee was diagnosed with acute myeloid leukaemia (AML) when she was 10 years old.  Here mum, Joanne, tells their story so far:

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Patient Story – Darren

Darren was diagnosed with acute myeloid leukaemia (AML) when he was 11 years old.  Now in his 30’s, Darren tells us how this has affected his life:

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Refining our knowledge about the genetic causes of leukaemia

A large number of genetic mutations have been identified in childhood AML, with any one child having between 5 and 20 mutations. The role played by these mutations, alone and in combination, is not fully understood. This project will develop a model system that will facilitate the study of these mutations. Ultimately this will aid the development of more effective ...

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A new treatment approach in acute myeloid leukaemia

Acute myeloid leukaemia is the second most common form of childhood leukaemia, with 100 children diagnosed every year in the UK. Around a third of these young patients cannot be saved with existing treatments. Dr Mussai is taking forward a new approach to treatment that could offer new hope to children with this devastating disease.
We are grateful to the ...

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Understanding how the leukaemia gene EVI1 affects children with Fanconi anaemia

Fanconi anaemia (FA) is a rare, inherited blood disorder that leads to bone marrow failure. Children with FA have a greatly increased risk of developing leukaemia. Dr Meyer’s research focuses on a gene called EVI1 which is involved in the development of leukaemia in children both with and without FA. He wants to understand how the FA genetic defect works ...

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