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  • Neuroblastoma

The developmental history of bilateral neuroblastoma

Sarah Farndon, UCL Institute of Child Health

Neuroblastoma is one of the most common solid tumours affecting children, and remains very difficult to treat. Several studies have already used Next Generation Sequencing (NGS) to examine somatic alterations (the changes in DNA which ...

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  • Brain and spinal tumours

Identification of new genetic changes in rhabdomyosarcoma

Professor Jill Birch, University of Manchester

Rhabdomyosarcoma (RMS) is a childhood cancer that develops in muscle, with 50 new cases every year in the UK. Older children in particular have a poor outlook and we need to improve our understanding of ...

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  • Acute Myeloid Leukaemia

A new treatment approach in acute myeloid leukaemia

Dr Francis Mussai, University of Birmingham

Acute myeloid leukaemia is the second most common form of childhood leukaemia, with 100 children diagnosed every year in the UK. Around a third of these young patients cannot be saved with existing treatments. Dr ...

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  • Brain and spinal tumours

Assessment of physical function in survivors of childhood bone and soft tissue tumours

Mr Craig Gerrand, Freeman Hospital

The treatment for bone and soft tissue tumours leaves many children disabled to some degree. We need to understand how these children manage after treatment in order that families get the necessary support to help ...

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  • Acute Lymphoblastic Leukaemia

The role of the leukaemic stem cell in disease relapse

Professor Tariq Enver, UCL Cancer Institute

* this project is being funded in collaboration with Great Ormond Street Hospital Children’s Charity, with each charity contributing 50% of the total cost of £284,15
Acute lymphoblastic leukaemia is the most common form of ...

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  • Wilm's Tumour

Advanced magnetic resonance imaging for improved diagnosis and prediction of treatment response in Wilms’ tumour patients

Professor Chris Clark, University College London

Wilms’ tumour is a cancer of the kidney, mostly affecting children under five. Overall survival rates are high, but there are different sub-types of Wilms’, and we can’t tell which type a child has without ...

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