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Patient Story – Zunairah

Zunairah was diagnosed with acute lymphoblastic leukaemia (ALL) on 20 January 2015. She was only one. Her dad Ayaze tells their story:

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Patient Story – Bella R

Bella was diagnosed with Acute lymphoblastic leukaemia in November 2016. She was just two years old at the time. Her mum, Lisa, tells their story so far:

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Immunotherapy for relapsed paediatric acute lymphoblastic leukaemia

Stem cell transplant is used as a treatment of last resort in young patients with acute lymphoblastic leukaemia (ALL) whose disease has failed to respond to or relapsed after chemotherapy. Only half of patients undergoing transplant are cured long-term, and disease relapse is the major cause of treatment failure. Professor Amrolia is pioneering the development of a new immunotherapy approach ...

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Patient Story – Neythra

 Neythra was diagnosed with acute lymphoblastic leukaemia in January 2014. Neythra shares her childhood cancer story:

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Investigations into the leukaemia gene EVI1 in children with Fanconi anaemia

Fanconi anaemia (FA) is a rare, inherited blood disorder that leads to bone marrow failure. Children with FA have a greatly increased risk of developing leukaemia. Dr Meyer’s research focuses on a gene called EVI1 which is involved in the development of leukaemia in children both with and without FA. He wants to understand how the FA genetic defect works together with EVI1 in ...

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Optimisation of the use of drugs in childhood acute lymphoblastic leukaemia

There is wide variability in the way that individual children metabolise different drugs. In this project, Professor Saha is setting out to tailor therapy to individual children based on their drug metabolism, adjusting both the dose and scheduling accordingly. We hope that this will help decrease the rates of both toxicity and disease recurrence.

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