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Patient Story – Lily

Lily was diagnosed with a optic pathway glioma, a type of brain tumour at the age of  one in November 2017 . Her mum Lianna tells their story so far: :

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£3m for childhood brain tumour research

Brain tumours account for a quarter of childhood cancer diagnoses and more than a third of childhood cancer deaths.
Childhood brain tumours are treated aggressively to give each child the very best chance of survival. But survival comes at a cost, and many young patients are left with devastating long-term and late effects that severely impact on their future health ...

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Identification of new genetic changes in rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a childhood cancer that develops in muscle, with 50 new cases every year in the UK. Older children in particular have a poor outlook and we need to improve our understanding of the disease in order to develop new approaches to treatment. Professor Birch is carrying out a detailed investigation of the genetic mutations underlying RMS development, ...

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Assessment of physical function in survivors of childhood bone and soft tissue tumours

The treatment for bone and soft tissue tumours leaves many children disabled to some degree. We need to understand how these children manage after treatment in order that families get the necessary support to help their child return to ‘normal’ life. The team in Newcastle is working on two devices that can be used to measure children’s physical activity and ...

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Studying stem cells in paediatric glioblastomas in search of new treatments

Professor Leach and his team are researching the cancer stem cells in paediatric glioblastoma. This brain tumour tends to resist treatment, and we need to find out why, so that life-saving new treatments can be developed to fight this extremely hard-to-treat cancer.
This project is studying cancer stem cells in paediatric gliobastomas, to help scientists look for new ways to help ...

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Understanding treatment-resistance and disease-spread in childhood gliomas

This project is looking paediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG), two brain tumours that affect children, and are currently incurable. To stop children dying from them, we need to learn more about how these tumours resist treatment and spread through the brain. Then we may be able to find new drugs to target and treat them.
We’re ...

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