An update from Children with Cancer UK. 7th January 2019
“We welcome the announcement of funding from NHS England for DNA testing for children with cancer to help select the best treatment.
Precision medicine has huge potential for treating cancer in a kinder, more effective way. This is particularly crucial for children, where the toxic treatments can have a serious impact on the long-term health and welfare of those who survive. That’s why since 2017 Children with Cancer UK has invested £3.74 million into pioneering work to put in place the infrastructure that we need for rapid sequencing of tumour DNA and to drive forward the implementation of precision medicine.
We call on NHS England to take this opportunity to significantly scale up access to routine genetic sequencing at all stages of treatment – particularly at relapse – and make precision medicine a reality for all children diagnosed with cancer.”
Grace and Louis’ guide to genetic testing and targeted treatments.
Childhood cancer survivor Louis and his twin sister Grace explain Precision Medicine.
You are helping us to fund £3.74m for this Precision Medicine research – an exciting new way to deliver cancer treatment to children. Thank you.
Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle.
This includes a personalised approach to cancer treatment which is tailored to the patient’s specific type of cancer. Scientists use state of the art genetic sequencing to identify key genetic and proteomic changes in a patient’s tumour.
These individual variations in genes allow doctors to allocate young patients to very focused tumour categories and prescribe treatments to their cancer’s individual makeup. As well as being more effective, highly targeted treatments are less likely to have toxic side effects.
Precision Medicine has two main goals:
Children with Cancer UK are helping to fund the development of a national infrastructure for rapid sequencing of tumour DNA from young cancer patients. This will include:
Our Precision Medicine project will actively offer Precision Medicine to young patients, who will benefit from rigorous diagnosis and highly targeted treatments.
The impact of the project will go much further than this:
Watch our Little Translators Grace and Louis explain Professor Chesler’s Precision Medicine research: