At the moment, we don’t know the cause of the blood cancers myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML) in many children. But in some rare cases of MDS/AML more than one family member is affected. These family sets give us valuable data in the search to identify the genetic factors in these diseases. In this project, Dr Tom is working with 26 such families to characterise these genetic mutations.
Rare blood cancers affecting more than one family member could help us discover what’s at the root of the genetic mutations causing them. This project is studying 26 affected families to help us learn more.
This research project on rare blood cancers has been successfully completed. Your donations allow us to fund ground-breaking research that can improve treatments given to children with cancer. Thank you. Your help allows us to continue to find ways to drive up the chances of survival for children with cancer and reduce the toxic side effects that can affect the rest of their lives.
Identification and characterisation of mutations that predispose to myelodysplastic syndrome and acute myeloid leukaemia
Dr Tom Vulliamy
Queen Mary University of London
London E1 2AT
1 April 2014