The cells of children’s and young people’s cancers often contain extra copies of chromosomes, known as aneuploidy, but it is not well understood why this occurs. Professor Christine Harrison and her team will investigate the underlying mechanisms that drive aneuploidy across many types of childhood cancers and how aneuploidy contributes to cancer formation. This could help doctors to better monitor patients and may also lead to us finding new ways to treat these types of cancer and potentially prevent certain cancers from developing in the first place.
This project is co-funded with Cancer Research UK as part of the Cancer Research UK–Children with Cancer UK Innovation Awards. Children with Cancer UK has contributed £487,624.30 towards this research project, the total cost of the project is £975,248.60
Aneuploidy is a driver of childhood cancer and a target for novel therapies.
Professor Christine Harrison, Professor Jonathan Higgins and Professor Steve Clifford
Newcastle, NE1 7RU