Neuroblastoma has a ‘high-risk’ form which, despite using every treatment available, means that some children can’t be cured. Some of these tumours have extra copies of the MYCN gene, and this could be important. So Dr Helen will be testing the effects of a new drug that we already use against ovarian cancer, and other similar drugs, on MYCN neuroblastoma. What we learn may help us develop new treatments quite quickly.
This project is looking at MYCN neuroblastoma to discover whether drugs that are already treating other types of cancer will be effective against it. It could quite quickly result in treatments that save the lives of more children.
Novel therapies for MYCN-amplified neuroblastoma
Dr Helen Bryant
University of Sheffield
Sheffield S10 2RX
1 September 2016
Alice was diagnosed with high-risk neuroblastoma a week before her second birthday. Watch the video to find out more about her story, as well finding out more about Dr Helen Bryant’s research project.