2019 Research Grant Call

2019 Research Grant Call for Research into Childhood Cancer Treatment and Survival.

15 projects were awarded grants totalling £3,265,328

Children with Cancer UK invited proposals for research projects and clinical PhD studentships that addressed improved treatment for and survival from childhood and young person cancer and into improved quality of ongoing life.

The deadline for proposals passed on 5th April 2019. We received a total of 50 preliminary proposals for our 2019 Research Grant Call for Research into Childhood Cancer Treatment and Survival.

Following initial triage by our Scientific Advisory Panel, 31 applicants were invited to submit full proposals, which were assessed by external peer review. Our Scientific Advisory Panel for this grant call met on 26th & 27th February 2020 to review these applications. Present at the meeting were Dr Chris Halsey, Dr Lynley Marshall, Dr Nick Goulden and Professor Roderick Skinner, Chaired by Dr Owen Williams.

Important Dates & Times

    Awards made

  • 29/11/2019

The following projects were awarded grants, totalling £3,265,328

Principal investigatorHost institutionGrant titleTotal
Professor Chris JonesInstitute of Cancer ResearchEvolutionary dynamics of MEK inhibitor sensitivity and resistance in diffuse midline glioma  £349,393
Professor Kathy Pritchard-JonesUCL Great Ormond Street Institute of Child HealthInternational benchmarking of childhood cancer survival by stage  £349,746.50
Dr Marc MansourUCL Cancer InstituteA novel immunotherapy target in T-cell acute lymphoblastic leukaemia (T-ALL)  £349,746.50
Dr Claire ClarkinUniversity of SouthamptonDeveloping 3-dimensional multicellular models of osteosarcoma  £49,984
Professor Mike HawkinsUniversity of BirminghamEstablish a comprehensive surveillance system for adverse health outcomes in British survivors of childhood, teenage and young adult cancer  £349,982.37
Professor Veronica KinslerUCL Great Ormond Street Institute of Child HealthIdentification of new therapies for melanoma in congenital melanocytic naevi – a universally fatal paediatric tumour  £249,755.76
Professor Anthony ChalmersUniversity of GlasgowIncreasing the susceptibility of neuroblastoma cells to radiotherapy by targeting glycolysis and lipogenesis  £249,774
Dr Sam BehjatiWellcome Sanger InstituteDevelopmental states of localised and metastatic osteosarcoma cells – a knowledge bank for novel biomarkers and therapeutic approaches  £349,418.96
Professor Julie IrvingNewcastle UniversityOptimising the use of repurposed drugs to improve the treatment of children with ALL  £213,259
Professor Steve CliffordNewcastle UniversitySMILE:  An International network for Medulloblastoma Survivorship and Late-Effects  £348,783.27
Professor John AndersonUCL Great Ormond Street Institute of Child HealthPilot to develop CRISPR library screen for enhanced function of G-D-T cells in paediatric solid cancers  £49,929.66
Dr Macarena Oporto EspuelasUCL Great Ormond Street Institute of Child HealthIdentification of novel surface antigen targets for CAR T cell strategies in paediatric Acute Myeloid Leukaemia stem cells  £220,000
Dr Defne SaatciUCL Great Ormond Street Institute of Child HealthInvestigating Late Effects of Surviving Childhood Cancer  £216,963.40
Dr John MurphyUniversity of WestminsterA pilot Investigation of the ZFP36L1 protein as a candidate therapeutic target in osteosarcoma cells  £14,013
Dr Raoul ReulenUniversity of BirminghamPilot study to investigate self-reported health behaviours in survivors of teenage and young adult cancer  £5,000


Children with Cancer UK is a member of the Association of Medical Research Charities (AMRC), which sets minimum standards of good practice to which member charities must adhere in their grant-making, including policies on peer review. We are also a member of the National Cancer Research Institute (NCRI), a partnership of UK cancer funders.
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