Constitutional Mismatch Repair Deficiency is a rare inherited cancer syndrome affecting children. Early diagnosis is important but challenging and the first symptoms often don’t appear to have anything to do with cancer. This project is looking at a new test that should allow us to identify children at risk – before they get cancer.
Because cancers are rare in children, and Hodgkin lymphoma usually shows as lumps in the neck and more general symptoms such as tiredness and night sweats, doctors often think it’s something common like glandular fever. A new blood test could make diagnosis easier.