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Supporting Acute Myeloid Leukaemia research

We’re funding a senior researcher to lead a new childhood leukaemia research team at the Paul O’Gorman Leukaemia Research Centre in Glasgow. The team will research the causes, mechanisms and treatment of childhood leukaemia, particularly looking at acute myeloid leukaemia (AML).

Our funding is providing vital support for a new team looking at childhood leukaemia, giving them the resources they need to help find better treatments for childhood AML.

Project Progress...

Tessa Holyoake

Project Details

  • Project Title

    Senior lecturer in translational paediatric haemopoiesis

  • Lead Researcher

    Professor Tessa Holyoake

  • Research Centre

    University of Glasgow

  • City & Institution Postcode

    Glasgow G12 0ZD

  • Start Date

    1 June 2012

  • Duration

    5 years

  • Grant Amount


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Andy, a teenager who was diagnosed with chronic myeloid leukaemia CML and is now in remission

Acute Myeloid Leukaemia

Information about acute myeloid leukaemia

Acute myeloid leukaemia (AML) accounts for 15% of childhood leukaemias and 5% of all childhood cancers.
Around 70 ...

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We helped to fund the cost of building and equipping the new Paul O’Gorman Leukaemia Research Centre in Glasgow, which opened in 2008.

It’s part of Glasgow’s Institute of Cancer Sciences (ICS), providing a highly interactive research environment where scientists and doctors work with the Beatson Institute of Cancer Research, the Royal Hospital for Sick Children and the Beatson West of Scotland Cancer Centre.

Now we’ve worked with Professor Tessa Holyoake, Director of the Paul O’Gorman Leukaemia Research Centre, to fund a new senior research post. The team will research the causes, mechanisms and treatment of childhood leukaemia, to help doctors improve how they treat children in the future.

They’ll look mainly at acute myeloid leukaemia (AML). AML accounts for only around 15 per cent of cases of childhood leukaemia, but we know less about it, so aren’t yet able to treat children with AML as effectively as we can treat those with acute lymphoblastic leukaemia (ALL). So there is an urgent need for better treatments.

What difference will this project make?

Because AML is much rarer than ALL, scientists can’t do the same large-scale studies of the disease in children. So they’ve had to use data and research results from adults and apply them to children. But we don’t really know whether the disease is the same in children as it is in adults.

At the Centre, the research team is focussed on understanding the similarities and differences between adult and childhood AML, so that treatments can be developed that target childhood AML more effectively.

Cancer research is expensive, involving costly equipment – so the funding we’re providing is essential to enable the team to carry out their day-to-day research activities.

The work of the new research team will help scientists and doctors understand more about the specific nature of childhood AML so that new, targeted treatments can be developed to give children affected by it a better chance of survival.

About the Research Team

The Paul O’Gorman Leukaemia Research Centre provides up-to-date facilities for research teams to work on new treatments for the benefit of all leukaemia patients – including children. Before this important centre opened, haematology research in Glasgow was scattered around six different sites with outdated equipment or inadequate facilities, making it very hard to join up NHS work, research and clinical activity.

We contributed £500,000 to help fund this major new leukaemia research centre.

Now we’ve worked with Professor Tessa Holyoake, Director of the Centre, to provide funding to support a senior research post in the Centre – to lead a programme of research into the causation and development of childhood leukaemia.

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