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A novel combination therapy to treat metastatic Ewing sarcoma

When Ewing sarcoma, a tumour of the bone, spreads to other parts of the body, it is difficult to treat and usually fatal. This project builds on previous work that has identified a promising new approach to treatment, combining two different types of drugs.
If successful, the team will take the new therapy forward to clinical trial.

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Developing immunotherapy for childhood sarcomas

Some childhood cancers don’t respond well to chemotherapy, but there is hope in the form of immunotherapy. Doctors have already achieved success using immunotherapy techniques to treat children with leukaemia and neuroblastoma. Now Professor John and his team aim to extend these techniques to treating childhood sarcomas.
For childhood cancers that don’t respond well to chemotherapy, immunotherapy offers new hope. Children ...

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Patient story – Scott

Scott was diagnosed with Ewing sarcoma, a rare type of bone cancer, when he was 12 years old. Six months later, after an aggressive course of chemotherapy, Scott lost his right leg to cancer. Now aged 21, Scott is a keen runner and competitive volleyball player, is in his third year of medical school and inspires many with his positive ...

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