New treatments are needed for osteosarcoma (OS), which is an aggressive type of bone cancer that mostly affects children and young adults. Reports suggest that the presence of immune cells, called macrophages, that circulate in the tumour help to improve survival, but it’s not known whether all patients would actually benefit from receiving drugs that activate the macrophages. Dr Claire Clarkin and her team are developing a laboratory model to study the mechanisms underlying this process and more effectively test new treatments.
Developing 3-dimensional multicellular models of osteosarcoma
Dr Claire Clarkin (wearing red coat)
University of Southampton
Southampton, SO17 1BJ
1 June 2021