One of the drugs used in the treatment of leukaemia is called Asparaginase, and helps in the treatment of many children. However, it can cause inflammation of the pancreas, and once children have developed this they can’t take it anymore. This project aims to find ways to protect pancreatic cells from the effects of this vital drug.
Our funding is helping doctors look at ways to protect pancreatic cells from the side-effects of a key anti-leukaemia drug, and offer alternative treatments to those children most likely to develop problems.
Pathophysiology of asparaginase associated pancreatitis
Dr Oleg Gerasimenko
Cardiff CF10 3AX
1 April 2015