Two radioactive drugs, called MIBG and LUDO, bind to the surfaces of neuroblastoma cells and are able to kill them when administered as single agents. Although these cancer-seeking, radioactive drugs have resulted in prolonged remission in patients, long-term cure of aggressive disease has not been achieved. Clinicians intend to improve the treatment of neuroblastoma by giving patients both MIBG and LUDO, increasing the likelihood of lethally irradiating all cancerous tissue in the body.
This research project on neuroblastoma has been successfully completed. Your donations allow us to fund ground-breaking research that can improve treatments given to children with cancer. Thank you. Your help allows us to continue to find ways to drive up the chances of survival for children with cancer and reduce the toxic side effects that can affect the rest of their lives.
Two radiopharmaceuticals for treatment of neuroblastoma
Professor Anthony Chalmers
University of Glasgow
1 August 2017