Children with Down syndrome (DS) have a greatly increased risk of developing leukaemia. All babies and children with DS have abnormalities that affect how their bodies produce blood cells, but leukaemia develops in only a minority of them. This project, taking advantage of the unparalleled power of new technologies, aims to find out why.
We’re funding this project to find out why Children with Down syndrome have a greatly increased risk of developing leukaemia. Professor Irene hopes that understanding this will help us prevent and treat leukaemia in all children in the future.
This research project on children with down syndrome have a greatly increased risk of developing leukaemia has been successfully completed. Your donations allow us to fund ground-breaking research that can improve treatments given to children with cancer. Thank you. Your help allows us to continue to find ways to drive up the chances of survival for children with cancer and reduce the toxic side effects that can affect the rest of their lives.
Global RNA profiles of trisomic, pre-leukaemic and leukaemic haemopoietic cells in Down syndrome
Professor Irene Roberts
University of Oxford
London NW1 7JR
1 June 2012
4 years 9 months