Fanconi anaemia (FA) is a rare, inherited blood disorder that leads to bone marrow failure. Children with FA have a greatly increased risk of developing leukaemia. Dr Meyer’s research focuses on a gene called EVI1 which is involved in the development of leukaemia in children both with and without FA. He wants to understand how the FA genetic defect works together with EVI1 in leukaemia development.
Our funding is helping Dr Stefan and his team find out how the EVI1 gene and the FA genetic defect combine to increase a child’s likelihood of developing leukaemia.
Investigations into the role of EVI1 in Fanconi anaemia associated malignant transformation
University of Manchester
29 March 2013
3 years 3 months